I had a TV set and a typewriter and that made me think a computer should be laid out like a typewriter with a video screen.
Who wants a stylus. You have to get em and put em away, and you lose em. Yuck. Nobody wants a stylus.
Using a mouse, keyboard or gamepad make my arm tired, so I can't use them in a continual manner. The only device I can use for an extended period of time is a joystick. It's posing problems when I'm test-playing something in progress.
For a while I was thinking about moving the mouse with my hand.
There is a reason why, on a DS, you get that little click when you press a button. There is a reason that it was important to have a microphone in the Wii Remote.
I don't think as a creator that I could create an experience that truly feels interactive if you don't have something to hold in your hand, if you don't have something like force feedback that you can feel from the controller.
The program should know if someone is at the keyboard or joystick or if it is just sitting there idle. It should know if someone is proficient in its use or a novice.