SETH MACFARLANE

I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time.

The trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science.

If a song is funny and absurd, and it sounds great, it's just going to be that much funnier. And there's no better example of that than 'Monty Python.'

Evolution doesn't care whether you believe in it or not, no more than gravity does. I want to rekindle excitement over what we've achieved as a species with the space program. We can't afford to regress back to the days of superstition.

I spent my entire childhood in the same town, in Kent. I went to grade school there. There was a boarding school that my mother taught at, called - appropriately enough - Kent School, that I went to. Yeah, pretty much my entire childhood was spent in that town.

I'll tell you what I think is not okay. Have you ever seen that show on MSNBC, 'Lockup?' It's a reality show that takes place inside a prison. Do the prisoners have to sign release forms? Or do they have to be on it whether they like it or not?

I'm one of the few people in Hollywood who actually had a good childhood.

You would not want me on your football team.

You don't want to be nasty for the sake of being nasty.

I have a car that I like - an Aston Martin - for Sunday drives in the country.

'American Dad' is, by its nature, much more political.

I wrote on a show called Johnny Bravo when I was at Hanna-Barbera.

On a certain day, I will tweet five times, and then I'll go four days without tweeting at all. It really depends on what time allows. Twitter, priority-wise, has to come after the work is done.

People do that on Facebook and it's the dumbest thing in the world. I don't care what your dinner looks like. Stop cluttering up the Internet with pictures of your dinner.

The problem with the cable networks is the lack of money, not from personal income but as far as show budget.

I love the English. My God, they brought us 'Benny Hill,' 'Monty Python,' 'The Office,' Neville Chamberlain.

I had - I was pretty hell bent on getting into the cartoon business specifically as an artist from the get-go.

There are people on staff who have made that point, that the upside to a second Bush term is that it makes 'American Dad' work better. To me, the price is too high. I would gladly give up the comedy to have a President Kerry. But you work with what you have.

I always thought it would be funny to have the Parents Television Council write an episode of 'Family Guy' and give them full creative control. Then see how good the episode is. That's something we've actually discussed in the writers' room. We haven't proposed it yet, but if somebody from the PTC reads this, it might be worth discussing.

The success of 'The Simpsons' really opened doors. It showed that if you were working in animation you didn't necessarily have to be working in kids' television.

There are times when I'm under the weather and the corporate machine tries to put me in the recording booth anyway. It's always up to me to say, 'Guys, listen to me, listen to what I sound like. I'm not myself.'

Denzel Washington has a great sense of humor. He did all those 'Nutty Professor' movies.

The way Disney characters move, they're very kind of slow and fluid and flowing; one pose kind of eases into the next. If you look at a show like 'The Simpsons' and subsequently a show like 'Family Guy' - the characters will jerk from pose to pose a lot, a bit more snappy. Which sort of goes along with the writing tone of the show.

I was a big Fred Flintstone fan.

I was a film major with a concentration in animation.